CD22+ T cells

Hi Everyone

We have recently seen several clinical cases where we see CD22+ CD3+ 
cells.	The current patient has a history of follicular lymphoma and 
~2y history of pancytopenia.  The BM aspirate did not show evidence 
of follicular lymphoma.  Rather it looks like there might be some T 
cell process going on.	The T cells have variable CD2, CD3, CD5 and 
CD7 expression; they are all CD4 CD8 double positive (8% of total 
events) and they are all CD22 positive. 

Any ideas or thoughts??

thanks, Jonni
-- 
Jonni S. Moore, Ph.D.
Professor of Pathology and Laboratory Medicine
Director, PATH BioRESOURCE
Director, Flow Cytometry and Cell Sorting Shared Resource, Abramson 
Cancer Center
Director, Clinical Flow Cytometry, Hospital of the University of Pennsylvania
University of Pennsylvania School of Medicine
220 John Morgan Bldg.
Philadelphia, PA  19104-6082
Phone:	215-898-6853
FAX:	215-573-0734