[ Ammonia Toxicity ]

Hi everyone,

Anyone has information regarding the mechanism of ammonia toxicity in cell 
culture flasks?  I do realize that the drop in pH due to ammonium ion 
build-up does play a role- can anyone elaborate?

Anita Persaud
ImClone Systems Incorporated


Confidentiality Note:  This e-mail, and any attachment to it, contains 
privileged and confidential information intended only for the use of the 
individual(s) or entity named on the e-mail.  If the reader of this e-mail 
is not the intended recipient, or the employee or agent responsible for 
delivering it to the intended recipient, you are hereby notified that 
reading it is strictly prohibited.  If you have received this e-mail in 
error, please immediately return it to the sender and delete it from your 
system.  Thank you.