Re: K562 Cell Line Surface Markers

Hi Fatima

If you have access to "the web" I would look at the ATCC site as this
contains quite a bit of information and references:

http://www.lgcpromochem-atcc.com/common/catalog/numSearch/numResults.cfm?atccNum=CCL-243#
26059

One of the references (Dimery IW , et al. Variation amongst K562 cell
cultures. Exp. Hematol. 11: 601-610, 1983.) heeds a note of caution, one
I would endorse from my experience of cell lines, in that even if it
says K562 on the vial it does not mean the cells will look or behave in
the same way as another vial of K562. This, to my mind, is one of the
concerns with working with cell lines. Although my understanding is that
cell lines purchased from ATCC are "true to type".

Good luck

Ian





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Ian Titley PhD
Section of Haemato-oncology
Institute of Cancer Research
15 Cotswold Road
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Tel +44 (0)20 7352 8133


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>>> "Fatema Legrand" <fatema.legrand@bn-immunotherapeutics.com>
13/12/2006 20:07:34 >>>
Hi everyone,

I was wondering if anyone was aware of whether the cell surface
markers
for the myelogenous leukemia cell line K562 have been characterized.

I would greatly appreciate any input you may have.


Kindest regards,

Fatema Legrand